Online Catalog
A collection of nonclinical studies & assays; customization is possible.

In vivo pharmacokinetics/pharmacodynamics (PK/PD)

Study

Metabolism

Characterizing the relationship between the pharmacokinetics (PK, concentration vs. time) and pharmacodynamics (PD, effect vs. time) is an important tool in the discovery and development of new drugs. 

The purpose of these studies is to provide a quantitative analysis of the dose-response relationships, describe the time-course effects, and determine efficacious dosing regimens.

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About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.