Online Catalog
A collection of nonclinical studies & assays; customization is possible.

Small interfering RNA (siRNA) quantitation

Analysis

Bioanalysis, LC-MS, IChem

Synthetic small interfering RNAs (siRNAs) can be introduced into a diverse range of organisms and cell types to induce degradation of MicroRNAs (mRNAs) with sequence complementarity, inducing short-term silencing of protein coding genes. RNA Interference (RNAi) has been used for applications that include gene function and pathway analysis, target identification and validation, and therapeutics. Quantitation of siRNAs in cells and animal tissues provides essential information on siRNA delivery efficiency, distribution, stability and specificity.

Molecule or Product Type

Biologics, Small Molecule

Regulatory

IND & CTA, NDA & BLA, Post-Market

Industry Market

Pharma

Phase

Clinical, Discovery, Nonclinical

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About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.